Oral and Maxillofacial Pathology Open access Peer reviewed

Where Inflammation Met Hamartoma: Radicular Cyst Associated With an Odontome in the Maxillary Anterior Region: A Case Report and Literature Review

Rohit Srikanthan, Ojasvi Sanjay Rambole, Suraj Sathyendra, Minati Jagadev and 1 more

European Journal of Dental and Oral Health | Aug 18, 2026

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What this paper is about

The diagnostic challenge posed by a mixed inflammatory and odontogenic hard-tissue lesion in the aesthetic zone is highlighted and the importance of complete enucleation, histopathologic confirmation, and defect reconstruction in managing extensive anterior maxillary lesions isunderscores.

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Radicular cysts are the most common inflammatory odontogenic cysts and usually arise in relation to a non-vital tooth, whereas odontomas arecommon benign mixed odontogenic lesions that are often discovered incidentally and treated with conservative surgical excision. The coexistence of a radicular cyst with an odontoma in the anterior maxilla appears uncommon in the available literature, making clinic-radiographic recognition and complete surgical management important for diagnosis and rehabilitation. A patient presented with pain and swelling in the upper anterior teeth region for 15 days, with no significant medical history. Clinical examination revealed a labial swelling extending from the right central incisor to the left lateral incisor and palatal swelling extending from the right central incisor to the right canine. Deep dentinal caries were present in both maxillary central incisors. Surgical management consisted of enucleation of the radicular cyst with removal of the odontome through a trapezoidal labial flap, with additional palatal flap elevation for complete retrieval of the odontome, followed by extraction of both central incisors and placement of platelet-rich fibrin with a bone graft before closure.This report highlights the diagnostic challenge posed by a mixed inflammatory and odontogenic hard-tissue lesion in the aesthetic zone and underscores the importance of complete enucleation, histopathologic confirmation, and defect reconstruction in managing extensive anterior maxillary lesions.

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Rohit Srikanthan

first | Rajarajeswari Dental College and Hospital

Ojasvi Sanjay Rambole

middle | Rajarajeswari Dental College and Hospital | ORCID 0009-0002-0978-4668

Suraj Sathyendra

middle | Rajarajeswari Dental College and Hospital

Minati Jagadev

middle | Rajarajeswari Dental College and Hospital

Mohammed Nahyan

last | Rajarajeswari Dental College and Hospital

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BibTeX

@article{Srikanthan2026Where,
  title = {Where Inflammation Met Hamartoma: Radicular Cyst Associated With an Odontome in the Maxillary Anterior Region: A Case Report and Literature Review},
  author = {Rohit Srikanthan and Ojasvi Sanjay Rambole and Suraj Sathyendra and Minati Jagadev and Mohammed Nahyan},
  journal = {European Journal of Dental and Oral Health},
  year = {2026},
  doi = {10.24018/ejdent.2026.7.4.70537},
  url = {https://doi.org/10.24018/ejdent.2026.7.4.70537}
}

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