Cerebrovascular and Carotid Artery Diseases
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Among patients with high-grade stenosis without recent symptoms, the addition of stenting led to a lower risk of a composite of perioperative stroke or death or ipsilateral stroke within 4 years than intensive medical management alone.
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Among patients with high-grade stenosis without recent symptoms, the addition of stenting led to a lower risk of a composite of perioperative stroke or death or ipsilateral stroke within 4 years than intensive medical management alone. Carotid endarterectomy did not lead to a significant benefit. (Funded by the National Institute of Neurological Disorders and Stroke and others; CREST-2 ClinicalTrials.gov number, NCT02089217.).
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@article{Lal2025Medical,
title = {Medical Management and Revascularization for Asymptomatic Carotid Stenosis},
author = {Brajesh K. Lal and Jenifer H. Voeks and Tanya N. Turan and Gary S. Roubin and Ronald M. Lazar and Robert D. Brown and John Huston and Lloyd J. Edwards and Michael Jones and Wayne M. Clark and Ángel Chamorro and Laura Llull and Carlos Mena‐Hurtado and Donald Heck and Randolph S. Marshall and Virginia J. Howard and Wesley S. Moore and Kevin M. Barrett and Bart M. Demaerschalk and Navdeep Sangha and Herbert D. Aronow and Thomas G. Brott and George Howard and Malcolm Foster and W. Charles Sternbergh and Fayaz A. Shawl and Giuseppe Lanzino and Joseph H. Rapp and Hoang S. Tran and Robert D. Ecker and Ariane Mackey and Vaqar Ali and Curtis A. Given and Philip Teal and Vikram S. Kashyap and Dipankar Mukherjee and Mark R. Harrigan and Scott Silverman and Matthew C. Koopmann and Virginia G. Wadley and Yu Zhang and J. Rhodes and Seemant Chaturvedi and James F. Meschia},
journal = {New England Journal of Medicine},
year = {2025},
doi = {10.1056/nejmoa2508800},
url = {https://doi.org/10.1056/nejmoa2508800}
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