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PCSK9 inhibition with evolocumab led to a lower risk of first cardiovascular events than placebo among patients with atherosclerosis or diabetes and without a previous myocardial infarction or stroke.
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PCSK9 inhibition with evolocumab led to a lower risk of first cardiovascular events than placebo among patients with atherosclerosis or diabetes and without a previous myocardial infarction or stroke. (Funded by Amgen; VESALIUS-CV ClinicalTrials.gov number, NCT03872401.).
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@article{Bohula2025Evolocumab,
title = {Evolocumab in Patients without a Previous Myocardial Infarction or Stroke},
author = {Erin A. Bohula and Nicholas A. Marston and Ajay Bhatia and Gaetano Maria De Ferrari and Lawrence A. Leiter and José Carlos Nicolau and Jeong-Gun Park and Julia Kuder and Sabina A. Murphy and Huei Wang and V. Bláha and Andrzej Budaj and Jan H. Cornel and Assen Goudev and Róbert Gábor Kiss and Alberto Lorenzatti and Alexander Parkhomenko and Marcoli Cyrille and Gabriel Paiva da Silva Lima and E. Magnus Ohman and Robert P. Giugliano and Marc S. Sabatine},
journal = {New England Journal of Medicine},
year = {2025},
doi = {10.1056/nejmoa2514428},
url = {https://doi.org/10.1056/nejmoa2514428}
}
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