Soft tissue tumors and treatment Open access Peer reviewed

Primary Tracheal Leiomyoma in a Dog: A Case Report

María Ezquerra-Durán, Maria Esther Durán-Flórez, Luis Javier Ezquerra, Pablo Cardenal-Morales and 1 more

Animals | Sep 7, 2026

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A 12-year-old spayed female Pit Bull was presented as an emergency because of an acute worsening of recurrent respiratory signs that were refractory to medical treatment, and Histopathological examination confirmed the diagnosis of tracheal leiomyoma.

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Primary tracheal neoplasia is uncommon in domestic animals and humans, and most reported tracheal tumors are malignant. To the authors’ knowledge, this case represents the third confirmed tracheal leiomyoma reported in dogs. Similarly, in human medicine, tracheal leiomyomas have only been reported sporadically and account for approximately 1% of tracheal tumors. A 12-year-old spayed female Pitbull was presented as an emergency because of worsening recurrent respiratory signs that were refractory to medical treatment. On initial evaluation, reduced mobility of both arytenoid cartilages was observed, and left arytenoid lateralization was therefore performed. However, the patient continued to experience severe episodes of respiratory distress requiring orotracheal intubation. Subsequent bronchoscopy revealed an intraluminal tracheal mass partially obstructing the airway lumen. Because of this obstruction, an emergency temporary tracheostomy was performed caudal to the mass. Once the patient was clinically stabilized, computed tomography was performed to complete surgical planning. Surgical treatment consisted of segmental tracheal resection and end-to-end anastomosis, with removal of 24% of the total tracheal length. Histopathological examination confirmed the diagnosis of tracheal leiomyoma. Complete surgical excision was achieved, supporting a favorable prognosis.

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María Ezquerra-Durán

first

Maria Esther Durán-Flórez

middle

Luis Javier Ezquerra

middle | ORCID 0000-0003-2536-9480

Pablo Cardenal-Morales

middle

Massimo Santella

last | ORCID 0000-0003-3722-8503

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@article{EzquerraDurn2026Primary,
  title = {Primary Tracheal Leiomyoma in a Dog: A Case Report},
  author = {María Ezquerra-Durán and Maria Esther Durán-Flórez and Luis Javier Ezquerra and Pablo Cardenal-Morales and Massimo Santella},
  journal = {Animals},
  year = {2026},
  doi = {10.3390/ani16172810},
  url = {https://doi.org/10.3390/ani16172810}
}

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