Traumatic Brain Injury and Neurovascular Disturbances
Peer reviewed
Abstract
Abstract
Background: Decompressive craniectomy (DC) is a life-saving intervention for severe traumatic brain injury (TBI), but often results in large cranial defects leading to syndrome of the trephined (ST)- a neurological condition characterized by headaches, cognitive decline, and motor deficits caused by atmospheric pressure acting on the unshielded brain. Case Description: This report describes a 45-year-old male who developed debilitating post-craniectomy headaches and cognitive deficits. While preoperative imaging suggested cerebral atrophy, the diagnosis of ST was confirmed by distinguishing reversible parenchymal compression from permanent atrophy, paradoxical herniation, and hydrocephalus. A custom 3D-printed titanium implant featuring a novel in situ -generated selenium nanoparticle (SeNP) surface was used to repair the defect. Following the procedure, the patient experienced a complete resolution of his headaches (Visual Analog Scale score 8/10 to 0/10) and a significant functional recovery. Conclusion: Postoperative imaging demonstrated rapid cerebral re-expansion and normalization of ventricular caliber, validating the mechanical etiology of the deficits. This case is unique in its application of nanostructured SeNP technology to enhance biocompatibility and highlights the importance of distinguishing dynamic compression from static atrophy in TBI recovery.
Direct answer
What can I do from this paper page?
Use this page to scan "Cranioplasty with a 3D-printed titanium implant for post-decompressive craniectomy syndrome: A case report" quickly: start with the summary and abstract, then check the authors, source, topics, and related papers. From here, open Scollr to follow Traumatic Brain Injury and Neurovascular Disturbances research, save the paper, or map adjacent work.
Research areas
Follow related topics
Citation
BibTeX
@article{Tran2026Cranioplasty,
title = {Cranioplasty with a 3D-printed titanium implant for post-decompressive craniectomy syndrome: A case report},
author = {Vuong Tran},
journal = {Surgical Neurology International},
year = {2026},
doi = {10.25259/sni_1167_2025},
url = {https://doi.org/10.25259/sni_1167_2025}
}FAQ
Using this paper in a discovery workflow
How do I find related work for this paper?
Use the related papers and topic links on this page as starting points. In Scollr, you can also open the paper and build a literature map around its references, citing papers, and related work.
How can I keep up with new Traumatic Brain Injury and Neurovascular Disturbances research papers?
Follow Traumatic Brain Injury and Neurovascular Disturbances research in Scollr. New papers from the topic flow into a personalized feed, and you can save useful studies to revisit later.
Can I cite this paper from this page?
This page includes a static BibTeX block for Cranioplasty with a 3D-printed titanium implant for post-decompressive craniectomy syndrome: A case report. Always verify the DOI, source, and publication details against the publisher record before submitting a manuscript.
Follow this research in Scollr
Follow the topics and authors behind this paper, save useful studies, and build a literature map when you are ready to go deeper.
Get the app