Peripheral Neuropathies and Disorders Open access Peer reviewed

Case Report: Recurrent Guillain–Barré Syndrome in a 56‐Year‐Old Male

Farah Sadiq, Shayan Nawaz, Moeez Ahmad Saeed, Fahad Bilal and 5 more

Clinical Case Reports | May 28, 2026

Abstract

Abstract

ABSTRACT Recurrent Guillain–Barré syndrome (GBS) is an uncommon variant of immune‐mediated polyradiculoneuropathy. We report a 56‐year‐old male who had two distinct episodes of acute inflammatory demyelinating neuropathy within the span of 3 months. The first episode presented with an episode of ascending paralysis and areflexia, with nerve conduction studies showing marked demyelination. He showed improvement after six sessions of plasma exchange. Three months later, he had a second acute relapse following a diarrheal illness, again demonstrating demyelinating changes. The infectious and metabolic workups were unremarkable. He responded to repeat plasma exchange and required no ventilatory support. This case emphasizes the importance of recognizing recurrent GBS and distinguishing it from acute‐onset CIPD, as timely immunotherapy remains critical in treatment.

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Authors

Researchers on this paper

Farah Sadiq

first | Lahore General Hospital | ORCID 0000-0002-1365-0235

Shayan Nawaz

middle | University of Lahore

Moeez Ahmad Saeed

middle | Punjab Medical College

Fahad Bilal

middle | Lahore General Hospital | ORCID 0009-0000-0470-5831

Hafiza Manahil Majeed

middle | Lahore General Hospital

Wasfa Shafiq

middle | Punjab Medical College

Kashaf Imtiaz

middle | Punjab Medical Center

Muhammad Husnain Ahmad

middle | University of Central Asia

Ali Gohar

last | Lahore General Hospital | ORCID 0000-0002-7357-1977

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Citation

BibTeX

@article{Sadiq2026Case,
  title = {Case Report: Recurrent Guillain–Barré Syndrome in a 56‐Year‐Old Male},
  author = {Farah Sadiq and Shayan Nawaz and Moeez Ahmad Saeed and Fahad Bilal and Hafiza Manahil Majeed and Wasfa Shafiq and Kashaf Imtiaz and Muhammad Husnain Ahmad and Ali Gohar},
  journal = {Clinical Case Reports},
  year = {2026},
  doi = {10.1002/ccr3.72817},
  url = {https://doi.org/10.1002/ccr3.72817}
}

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