Antioxidant Activity and Oxidative Stress Open access Peer reviewed

Unlocking the potential of carotenoids produced by Phaffia rhodozyma: insights into sustainable biorefinery, health benefits and potential applications

Pedro Garcia Pereira Silva, Janaína Fernandes de Medeiros Burkert, Lucielen Oliveira Santos

Journal of Food Science and Technology | Jul 23, 2026

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The intrinsic value of P. rhodozyma biomass as a renewable source of high-value carotenoids, especially astaxanthin is highlighted, and the potential health-promoting properties of these compounds are discussed, including antioxidant, anti-inflammatory, and immunomodulatory activities.

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Abstract This review provides a comprehensive and updated overview of recent advances in the production of carotenoids by the yeast Phaffia rhodozyma within the context of white biotechnology. Emphasis is placed on its role in sustainable biorefinery processes, the associated health benefits of its metabolites, and their potential industrial applications. In contrast to conventional reviews, which typically focus on optimizing fermentation parameters or improving extraction methods, this study highlights the intrinsic value of P. rhodozyma biomass as a renewable source of high-value carotenoids, especially astaxanthin. The potential health-promoting properties of these compounds are discussed, including antioxidant, anti-inflammatory, and immunomodulatory activities. Furthermore, the review addresses current market trends and examines the contribution of P. rhodozyma to the development of sustainable biorefineries and industrial bioprocesses.

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Pedro Garcia Pereira Silva

first | Universidade Federal do Rio Grande | ORCID 0000-0002-2623-9744

Janaína Fernandes de Medeiros Burkert

middle | Universidade Federal do Rio Grande | ORCID 0000-0002-8504-5376

Lucielen Oliveira Santos

last | Universidade Federal do Rio Grande | ORCID 0000-0003-1459-9715

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BibTeX

@article{Silva2026Unlocking,
  title = {Unlocking the potential of carotenoids produced by Phaffia rhodozyma: insights into sustainable biorefinery, health benefits and potential applications},
  author = {Pedro Garcia Pereira Silva and Janaína Fernandes de Medeiros Burkert and Lucielen Oliveira Santos},
  journal = {Journal of Food Science and Technology},
  year = {2026},
  doi = {10.1007/s13197-026-06825-2},
  url = {https://doi.org/10.1007/s13197-026-06825-2}
}

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