Mechanical Circulatory Support Devices
Open access
Peer reviewed
Abstract
Abstract
The use of left ventricular assist device (LVAD) implantation for destination therapy (DT) has been recently increased worldwide. In 2021, DT was also approved in Japan. Here, we report a single-institution experience of LVAD implantation for DT. This retrospective observational study was conducted at Osaka University Medical Hospital in Japan. Forty patients who underwent LVAD implantation for DT were included. The primary endpoint was on-device survival, and the secondary endpoint was the incidence of LVAD-related complications at five years. The on-device survival rates were 82.3%, 73.3%, and 49.8% at 1, 3, and 5 years, respectively. Most patients (90.6%) experienced rehospitalization during the follow-up period and the most common cause was LVAD-related infection. One-quarter of the patients (10 cases) required LVAD pump exchange, also most commonly due to LVAD-related infection. Comparative analysis with 213 patients who underwent LVAD implantation for bridge to transplant (BTT) revealed no significant change in the primary and secondary outcomes. Our results demonstrate favorable clinical outcomes for LVAD implantation for DT in this Japanese cohort.
Direct answer
What can I do from this paper page?
Use this page to scan "Clinical differences between destination therapy and bridge-to-transplant left ventricular assist device implantation: a 17-year single-center experience in Japan" quickly: start with the summary and abstract, then check the authors, source, topics, and related papers. From here, open Scollr to follow Mechanical Circulatory Support Devices research, save the paper, or map adjacent work.
Research areas
Follow related topics
Citation
BibTeX
@article{Inoue2026Clinical,
title = {Clinical differences between destination therapy and bridge-to-transplant left ventricular assist device implantation: a 17-year single-center experience in Japan},
author = {Kōichi Inoue and Daisuke Yoshioka and Yusuke Misumi and Ai Kawamura and Shin Yajima and Takuji Kawamura and Shunsuke Saito and Takashi Yamauchi and Shigeru Miyagawa},
journal = {Journal of Artificial Organs},
year = {2026},
doi = {10.1007/s10047-026-01581-8},
url = {https://doi.org/10.1007/s10047-026-01581-8}
}FAQ
Using this paper in a discovery workflow
How do I find related work for this paper?
Use the related papers and topic links on this page as starting points. In Scollr, you can also open the paper and build a literature map around its references, citing papers, and related work.
How can I keep up with new Mechanical Circulatory Support Devices research papers?
Follow Mechanical Circulatory Support Devices research in Scollr. New papers from the topic flow into a personalized feed, and you can save useful studies to revisit later.
Can I cite this paper from this page?
This page includes a static BibTeX block for Clinical differences between destination therapy and bridge-to-transplant left ventricular assist device implantation: a 17-year single-center experience in Japan. Always verify the DOI, source, and publication details against the publisher record before submitting a manuscript.
Follow this research in Scollr
Follow the topics and authors behind this paper, save useful studies, and build a literature map when you are ready to go deeper.
Get the app