Hernia repair and management
Open access
Peer reviewed
Scollr summary
What this paper is about
Comparative analyses indicate OviTex performs similarly to synthetic mesh regarding hernia recurrence and surgical site infection rates, and may be preferable in patients with increased risk factors or prior mesh infection.
Full abstract
Read the full abstract
INTRODUCTION: mesh is a reinforced tissue matrix (RTM) that combines biologic and synthetic components, aiming to reduce inflammatory response while providing durable abdominal wall support. Comparative analyses indicate it performs similarly to synthetic mesh regarding hernia recurrence and surgical site infection rates, and may be preferable in patients with increased risk factors or prior mesh infection. This systematic review and meta-analysis evaluated the efficacy and safety profile of OviTex, particularly in patients undergoing ventral hernia repair (VHR). METHODS: Following PRISMA guidelines, we searched PubMed, Embase, Scopus, and ClinicalTrials.gov from inception to September 2025. Studies comparing the use of OviTex in VHR with synthetic or other biologic meshes were included. The primary endpoint was recurrence rates. Secondary outcomes were surgical site occurrences (SSO) and hospital length of stay (LOS). Statistical analysis was performed with Review Manager 5.4 using a random-effects model. RESULTS: . An open approach was specified in 171 (32%) cases. The overall primary fascial closure rate was 88%, with mesh most frequently placed in the retromuscular (39%) or intraperitoneal (35%) planes. Overall analysis showed significantly reduced recurrence rates (RR 0.45; 95% CI 0.22 to 0.94; p = 0.03) for patients using OviTex when compared with synthetic or other biologic meshes. There were no significant differences regarding SSO rates (RR 1.27; 95% CI 0.79 to 2.05; p = 0.32) and LOS (MD 3.18 days; 95% CI -6.38 to 12.74 days; p = 0.51) between groups. CONCLUSION: for ventral hernia repair. Preliminary evidence indicates lower rates of recurrence at a mean follow-up of 19.3 months and comparable outcomes in terms of surgical site occurrences and length of stay. However, these findings are based on a limited number of observational studies, and further prospective research with longer follow-up is needed to confirm reinforced tissue matrices as a reliable alternative in patients at higher risk.
Direct answer
What can I do from this paper page?
Use this page to scan "Efficacy and safety of ovine reinforced tissue matrix for ventral hernia repair: a systematic review and meta-analysis" quickly: start with the summary and abstract, then check the authors, source, topics, and related papers. From here, open Scollr to follow Hernia repair and management research, save the paper, or map adjacent work.
Research areas
Follow related topics
Citation
BibTeX
@article{Lima2026Efficacy,
title = {Efficacy and safety of ovine reinforced tissue matrix for ventral hernia repair: a systematic review and meta-analysis},
author = {Diego Laurentino Lima and Maria Clara Morais and Augusto Graziani e Sousa and Lorraine Michelle da Silva de Almeida and Leticia Graciolli and Eduardo Parra‐Dávila and Salvador Morales-Conde and Flavio Malcher},
journal = {Hernia},
year = {2026},
doi = {10.1007/s10029-026-03817-1},
url = {https://doi.org/10.1007/s10029-026-03817-1}
}FAQ
Using this paper in a discovery workflow
How do I find related work for this paper?
Use the related papers and topic links on this page as starting points. In Scollr, you can also open the paper and build a literature map around its references, citing papers, and related work.
How can I keep up with new Hernia repair and management research papers?
Follow Hernia repair and management research in Scollr. New papers from the topic flow into a personalized feed, and you can save useful studies to revisit later.
Can I cite this paper from this page?
This page includes a static BibTeX block for Efficacy and safety of ovine reinforced tissue matrix for ventral hernia repair: a systematic review and meta-analysis. Always verify the DOI, source, and publication details against the publisher record before submitting a manuscript.
Follow this research in Scollr
Follow the topics and authors behind this paper, save useful studies, and build a literature map when you are ready to go deeper.
Get the app