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Synchrotron X-ray multi-projection imaging (XMPI) for high-resolution 4D characterization of multiphase flows

Tomas Rosén, Zisheng Yao, Jonas Tejbo, Patrick Wegele and 14 more

Experiments in Fluids | Jul 23, 2026 | 1 citation

Abstract

Abstract

Multiphase flows where particles, bubbles, or droplets are suspended in a fluid govern critical processes in biology, medicine, materials processing, and geophysics. However, observing their microscale dynamics in opaque systems has remained a fundamental challenge. We present Synchrotron X-ray Multi-Projection Imaging (XMPI), a novel approach enabling four-dimensional (3D + time) tracking of microparticles in visibly opaque suspension flows without requiring sample rotation. By capturing simultaneous projections from multiple angles using beam-split X-rays at synchrotron facilities, we resolve instantaneous particle positions and trajectories in opaque fluids such as blood. We demonstrate the potential of XMPI through individual particle tracking velocimetry (3D PTV) in dilute conditions, as well as multi-projection image velocimetry in dense suspensions. The methodology provides otherwise inaccessible experimental validation for particle-resolved computational fluid dynamics models and allows, e.g., observation of inertial focusing effects and microstructural dynamics relevant to suspension rheology and biomedical flows. This work paves the way for high-resolution, time-resolved 4D imaging of complex multiphase flows across a range of scientific and industrial applications. Combining XMPI with recent AI-supported 4D reconstruction algorithms opens a new spatiotemporal frontier for high-speed, rotation-free microtomography.

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Authors

Researchers on this paper

Tomas Rosén

first | KTH Royal Institute of Technology

Zisheng Yao

middle | Lund University | ORCID 0000-0001-7970-2133

Jonas Tejbo

middle | KTH Royal Institute of Technology

Patrick Wegele

middle | KTH Royal Institute of Technology

Julia Rogalinski

middle | Lund University | ORCID 0009-0008-7133-619X

Frida Nilsson

middle | KTH Royal Institute of Technology | ORCID 0000-0001-9503-9300

Kannara Mom

middle | Techniques of Informatics and Microelectronics for Integrated Systems Architecture | ORCID 0000-0002-8964-6718

Zhe Hu

middle | Lund University | ORCID 0000-0002-4277-6427

Samuel McDonald

middle | Lund University | ORCID 0000-0002-0904-0477

Kim Nygård

middle | Lund University | ORCID 0000-0002-4906-0093

A. Mazzolari

middle | University of Ferrara | ORCID 0000-0003-0804-6778

Alexander Groetsch

middle | KTH Royal Institute of Technology | ORCID 0000-0002-0566-1532

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Citation

BibTeX

@article{Rosn2026Synchrotron,
  title = {Synchrotron X-ray multi-projection imaging (XMPI) for high-resolution 4D characterization of multiphase flows},
  author = {Tomas Rosén and Zisheng Yao and Jonas Tejbo and Patrick Wegele and Julia Rogalinski and Frida Nilsson and Kannara Mom and Zhe Hu and Samuel McDonald and Kim Nygård and A. Mazzolari and Alexander Groetsch and Korneliya Gordeyeva and Daniel Söderberg and Fredrik Lundell and Lisa Prahl Wittberg and E. M. Asimakopoulou and Pablo Villanueva‐Perez},
  journal = {Experiments in Fluids},
  year = {2026},
  doi = {10.1007/s00348-026-04271-6},
  url = {https://doi.org/10.1007/s00348-026-04271-6}
}

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