Soft tissue tumors and treatment
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A 51-year-old man with a GGT in the gastric antrum who underwent 6-year multimodal imaging follow-up, including CT, MRI, and serial endoscopic ultrasonography, highlights that GGT may exhibit characteristic yet dynamic imaging features on long-term follow-up.
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Gastric glomus tumor (GGT) is a rare mesenchymal neoplasm with nonspecific clinical and imaging features, often leading to preoperative misdiagnosis. Its longitudinal imaging evolution remains poorly characterized. Herein, we report a 51-year-old man with a GGT in the gastric antrum who underwent 6-year multimodal imaging follow-up, including CT, MRI, and serial endoscopic ultrasonography (EUS). The lesion presented as a well-circumscribed subepithelial nodule with marked and persistent enhancement on CT. It showed slightly low signal intensity on T1-weighted imaging, slightly high signal intensity on T2-weighted imaging, and mild early arterial enhancement followed by persistent marked enhancement on dynamic contrast-enhanced MRI. Over the 6-year follow-up, the lesion showed an overall increase in size and a transition from a homogeneous to a heterogeneous hypoechoic appearance on serial EUS. It was initially misdiagnosed as a gastrointestinal stromal tumor. Histopathology confirmed the diagnosis of GGT. This case highlights that GGT may exhibit characteristic yet dynamic imaging features on long-term follow-up. Recognition of these features across modalities may improve preoperative diagnostic accuracy.
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@article{Jiang2026Case,
title = {Case Report: Gastric glomus tumor with long-term dynamic multimodal imaging findings},
author = {Yujun Jiang and Wenli Lian and Xiaochen Dong and Xueyan Jia and Qingxia Xu and Min Wang and Zhongcheng Hang and Xuan Yang},
journal = {Frontiers in Oncology},
year = {2026},
doi = {10.3389/fonc.2026.1932357},
url = {https://doi.org/10.3389/fonc.2026.1932357}
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