Parkinson's Disease and Spinal Disorders Open access Peer reviewed

Paraneoplastik Miyastenia Gravis'te Titin Pozitifliğinin Rolü

Recai Orak, Müttalip Özbek, Mehmet Ufuk Aluçlu

Dicle Medical Journal / Dicle Tip Dergisi | Sep 10, 2026

Abstract

Abstract

Miyastenia gravis (MG), klinik gidişatı büyük ölçüde otoantikor profiliyle şekillenen otoimmün bir hastalıktır. Özellikle ileri yaş başlangıçlı olgularda ve timoma varlığında saptanan anti-titin antikorlarının, hastalık şiddeti ve kötü prognozla doğrudan ilişkili olduğu bilinmektedir. Bu olgu serisinde, geleneksel tanı testlerinin yetersiz kalabildiği atipik paraneoplastik MG vakalarında anti-titin antikorlarının tanısal değeri ve klinik yönetimdeki kritik rolüne dikkat çekilmesi amaçlanmıştır.

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Authors

Researchers on this paper

Recai Orak

first | Dicle University

Müttalip Özbek

middle | Dicle University | ORCID 0000-0001-7413-0965

Mehmet Ufuk Aluçlu

last | Dicle University | ORCID 0000-0001-5876-8643

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Citation

BibTeX

@article{Orak2026Paraneoplastik,
  title = {Paraneoplastik Miyastenia Gravis'te Titin Pozitifliğinin Rolü},
  author = {Recai Orak and Müttalip Özbek and Mehmet Ufuk Aluçlu},
  journal = {Dicle Medical Journal / Dicle Tip Dergisi},
  year = {2026},
  doi = {10.5798/dicletip.2037439},
  url = {https://doi.org/10.5798/dicletip.2037439}
}

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