Neural and Behavioral Psychology Studies

Dynamic geometry remapping of neural activity within frontal and subcortical areas during decision-making

Frederic M. Stoll, Neelima Valluru, Peter H. Rudebeck

bioRxiv (Cold Spring Harbor Laboratory) | Jun 16, 2026

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Recording 16,495 neurons across nine frontal and subcortical areas in macaques revealed brain-wide fluctuations between encoding the attributes of available options, showing dynamic representations track deliberation and scale with decision difficulty.

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ABSTRACT Decision-making involves dynamic evaluation of competing options. Recording 16,495 neurons across nine frontal and subcortical areas in macaques revealed brain-wide fluctuations between encoding the attributes of available options. These dynamic representations track deliberation and scale with decision difficulty. Instead of binding attribute information of different options together, our analyses show that these representations are associated with dynamic area- and attribute-specific changes in neural geometry.

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Frederic M. Stoll

first | Allen Institute for Brain Science | ORCID 0000-0002-8642-8133

Neelima Valluru

middle | Allen Institute for Brain Science

Peter H. Rudebeck

last | Allen Institute for Brain Science | ORCID 0000-0002-1411-7555

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BibTeX

@article{Stoll2026Dynamic,
  title = {Dynamic geometry remapping of neural activity within frontal and subcortical areas during decision-making},
  author = {Frederic M. Stoll and Neelima Valluru and Peter H. Rudebeck},
  journal = {bioRxiv (Cold Spring Harbor Laboratory)},
  year = {2026},
  doi = {10.64898/2026.06.11.731612},
  url = {https://doi.org/10.64898/2026.06.11.731612}
}

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