Gastric Cancer Management and Outcomes
Peer reviewed
Scollr summary
What this paper is about
The FAMISH score was significantly associated with MGL development after endoscopic resection in Japanese patients, and may have potential to provide additional information for risk stratification in guiding post-ER surveillance.
Full abstract
Read the full abstract
Purpose Endoscopic submucosal dissection (ESD) is a curative treatment for early gastric cancer (EGC); however, the risk of metachronous gastric lesions (MGL) persists. The FAMISH score was recently developed in Europe to stratify MGL risk, but its external validity in Japanese patients remains unclear. We aimed to externally validate the FAMISH score in a Japanese cohort undergoing endoscopic resection.Methods We retrospectively analyzed patients who underwent endoscopic resection between 2005 and 2024. The FAMISH score (0–9), based on six clinical and endoscopic variables, was calculated for each patient. Predictive performance for MGL was assessed using receiver operating characteristic (ROC) analysis and cumulative incidence analyses with and without competing risks.Results A total of 387 patients were included (non-MGL: 320; MGL: 67). The MGL group had significantly higher FAMISH scores, both in the proportion with scores ≥3 (82.1% vs. 65.6%, p = 0.01) and in median score (5.0 vs. 3.0, p < 0.01). ROC analysis showed modest discrimination (AUC 0.657, 95% CI 0.586–0.728). A cutoff ≥3 yielded 82.1% sensitivity and 34.4% specificity. Competing-risk analysis demonstrated significantly higher cumulative incidence in the high-score group (Gray’s test, p = 0.007), and Kaplan–Meier analysis showed similar results (log-rank p = 0.010).Conclusions The FAMISH score was significantly associated with MGL development after endoscopic resection in Japanese patients. Despite its modest discriminatory performance, the FAMISH score may have potential to provide additional information for risk stratification; however, its clinical utility in guiding post-ER surveillance remains to be established.
Direct answer
What can I do from this paper page?
Use this page to scan "FAMISH score for predicting metachronous gastric lesions after endoscopic resection: validation in Japanese patients" quickly: start with the summary and abstract, then check the authors, source, topics, and related papers. From here, open Scollr to follow Gastric Cancer Management and Outcomes research, save the paper, or map adjacent work.
Research areas
Follow related topics
Citation
BibTeX
@article{Terada2026FAMISH,
title = {FAMISH score for predicting metachronous gastric lesions after endoscopic resection: validation in Japanese patients},
author = {Rie Terada and Yu Takahashi and Tomomi Kamidaki and Akiko Haruta and Haruhisa Suzuki and Hirofumi Kogure},
journal = {Scandinavian Journal of Gastroenterology},
year = {2026},
doi = {10.1080/00365521.2026.2724328},
url = {https://doi.org/10.1080/00365521.2026.2724328}
}FAQ
Using this paper in a discovery workflow
How do I find related work for this paper?
Use the related papers and topic links on this page as starting points. In Scollr, you can also open the paper and build a literature map around its references, citing papers, and related work.
How can I keep up with new Gastric Cancer Management and Outcomes research papers?
Follow Gastric Cancer Management and Outcomes research in Scollr. New papers from the topic flow into a personalized feed, and you can save useful studies to revisit later.
Can I cite this paper from this page?
This page includes a static BibTeX block for FAMISH score for predicting metachronous gastric lesions after endoscopic resection: validation in Japanese patients. Always verify the DOI, source, and publication details against the publisher record before submitting a manuscript.
Follow this research in Scollr
Follow the topics and authors behind this paper, save useful studies, and build a literature map when you are ready to go deeper.
Get the app