Dialysis and Renal Disease Management
Open access
Peer reviewed
Abstract
Abstract
Social alienation severely impairs the mental health and quality of life of patients undergoing maintenance hemodialysis (MHD). However, most studies conducted have been variable-centered, group-level analyses, which cannot capture inherent heterogeneity in social alienation, hindering the development of precise intervention strategies. To address this, this study applied the biopsychosocial (BPS) model to investigate latent profiles of social alienation and their influencing factors in patients undergoing MHD. A cross-sectional survey was conducted using convenience sampling among patients receiving maintenance dialysis at a tertiary care hospital in Southwest China from January to May 2025. Data were collected using a general information questionnaire, the General Alienation Scale, and the General Self-Efficacy Scale. Potential classes of social alienation were identified by latent profile analysis (LPA). Univariate analysis and binary logistic regression were employed to identify influencing factors. Among the 283 valid questionnaires, LPA identified two profiles of social alienation: a low-risk adaptive subgroup (71.7%) and a high-risk impaired subgroup (28.3%). Logistic regression analysis indicated that insurance type, perceived economic burden, and self-efficacy may be influencing factors of the latent profile of social alienation (all P < 0.05). Heterogeneity exists in the social alienation of MHD patients. Inadequate health insurance coverage, heavy economic burden, and low self-efficacy may be associated with high-risk social alienation. Therefore, healthcare professionals should develop and implement hierarchical and individualized intervention strategies based on the influencing factors of different latent profiles.
Direct answer
What can I do from this paper page?
Use this page to scan "Latent profile analysis of social alienation and its influencing factors in patients undergoing maintenance hemodialysis" quickly: start with the summary and abstract, then check the authors, source, topics, and related papers. From here, open Scollr to follow Dialysis and Renal Disease Management research, save the paper, or map adjacent work.
Research areas
Follow related topics
Citation
BibTeX
@article{Liu2026Latent,
title = {Latent profile analysis of social alienation and its influencing factors in patients undergoing maintenance hemodialysis},
author = {Yuanyuan Liu and Chunlin Wu and Yan Yu and Tianzhi Liao},
journal = {Scientific Reports},
year = {2026},
doi = {10.1038/s41598-026-63830-3},
url = {https://doi.org/10.1038/s41598-026-63830-3}
}FAQ
Using this paper in a discovery workflow
How do I find related work for this paper?
Use the related papers and topic links on this page as starting points. In Scollr, you can also open the paper and build a literature map around its references, citing papers, and related work.
How can I keep up with new Dialysis and Renal Disease Management research papers?
Follow Dialysis and Renal Disease Management research in Scollr. New papers from the topic flow into a personalized feed, and you can save useful studies to revisit later.
Can I cite this paper from this page?
This page includes a static BibTeX block for Latent profile analysis of social alienation and its influencing factors in patients undergoing maintenance hemodialysis. Always verify the DOI, source, and publication details against the publisher record before submitting a manuscript.
Follow this research in Scollr
Follow the topics and authors behind this paper, save useful studies, and build a literature map when you are ready to go deeper.
Get the app