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Self-care profiles and quality of life trajectories in patients with chronic heart failure-caregiver dyads: a prospective cohort study

Lei He, Qiao Zhen, Rulan Yin, Ying Zhao and 4 more

BMC Nursing | Jul 1, 2026

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The necessity for profile-specific interventions tailored to the unique characteristics of each dyad to mitigate quality of life deterioration is underscore the necessity for profile-specific interventions tailored to the unique characteristics of each dyad to mitigate quality of life deterioration.

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BACKGROUND: Chronic heart failure requires effective dyadic self-care management, yet the longitudinal relationship between distinct dyadic self-care profiles and quality of life trajectories remains unclear. This study aimed to identify distinct self-care profiles in chronic heart failure patient-caregiver dyads and examine their associations with quality of life trajectories from hospitalization to three months post-discharge. METHODS: This prospective cohort study enrolled 330 patient-caregiver dyads with chronic heart failure. Data were collected at hospitalization, one month, and three months post-discharge via the Self-Care of Heart Failure Index and the Caregiver Contribution to Self-Care of Heart Failure Index for dyadic self-care, the Minnesota Living with Heart Failure Questionnaire for patient quality of life, and the Family Caregiver Quality of Life scale for caregiver quality of life. Latent class analysis was used to identify dyadic self-care profiles, and generalized estimating equations were employed to examine longitudinal associations. RESULTS: Latent class analysis revealed three distinct dyadic self-care profiles: dyadic dependent (23.94%), dyadic passive (49.39%), and dyadic active (26.67%). Using generalized estimating equations, we found that at 3 months post-discharge, patients in the Dyadic Active group had a significantly lower total Minnesota Living with Heart Failure Questionnaire score (67.6, indicating better quality of life, than did those in the Dependent (77.6, P < 0.001) and Passive (77.1, P < 0.001) groups. Caregivers in the Dyadic Active group maintained stable Family Caregiver Quality of Life scale scores over time (P = 0.210), whereas those in the other two groups experienced significant decreases (P < 0.001). CONCLUSIONS: Distinct self-care profiles are associated with significantly different quality of life trajectories for chronic heart failure patients and their caregivers. These findings underscore the necessity for profile-specific interventions tailored to the unique characteristics of each dyad to mitigate quality of life deterioration. CLINICAL TRIAL NUMBER: Not applicable.

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Authors

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Lei He

first | Soochow University | ORCID 0009-0009-4011-5543

Qiao Zhen

middle | Soochow University

Rulan Yin

middle | Soochow University

Ying Zhao

middle | Soochow University

Li J

middle | Soochow University | ORCID 0000-0003-1338-8764

Li Yun Shang

middle | Soochow University

Min Xia Lu

middle | Soochow University

Xiao Qing Shi

last | Soochow University

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BibTeX

@article{He2026Self,
  title = {Self-care profiles and quality of life trajectories in patients with chronic heart failure-caregiver dyads: a prospective cohort study},
  author = {Lei He and Qiao Zhen and Rulan Yin and Ying Zhao and Li J and Li Yun Shang and Min Xia Lu and Xiao Qing Shi},
  journal = {BMC Nursing},
  year = {2026},
  doi = {10.1186/s12912-026-04963-8},
  url = {https://doi.org/10.1186/s12912-026-04963-8}
}

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