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An Unusual Case of Sudden Cardiac Death due to Right Coronary Artery Anomaly During the Valsalva Manoeuvre: A Case Report and Literature Review

Rosario Barranco, Gabriele Gaggero, Francesco Ventura

Academic Forensic Pathology | Aug 12, 2026

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A rare case of sudden cardiac death of a 27-year-old man due to a RCA with origin from the left coronary sinus and abnormal course, exacerbated by the Valsalva manoeuvre during defaecation is presented.

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Background: Coronary artery anomalies (CAAs) represent one of the most complex pathologies in cardiology. Right coronary artery anomaly (RCA) is extremely rare. Often this condition is asymptomatic and diagnosed accidentally; however, in some cases it can have a catastrophic onset and cause sudden death. Case Report: We present here a rare case of sudden cardiac death (SCD) of a 27-year-old man due to a RCA with origin from the left coronary sinus and abnormal course, exacerbated by the Valsalva manoeuvre during defaecation. Conclusion: We emphasise the need for a careful and comprehensive approach in cases of SCD. In these cases, a careful and thorough analysis of the origin and course of the coronary arteries is necessary.

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Rosario Barranco

first | Ospedale Policlinico San Martino | ORCID 0000-0002-2838-7716

Gabriele Gaggero

middle | Istituto Giannina Gaslini | ORCID 0000-0001-9098-563X

Francesco Ventura

last | Ospedale Policlinico San Martino

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@article{Barranco2026Unusual,
  title = {An Unusual Case of Sudden Cardiac Death due to Right Coronary Artery Anomaly During the Valsalva Manoeuvre: A Case Report and Literature Review},
  author = {Rosario Barranco and Gabriele Gaggero and Francesco Ventura},
  journal = {Academic Forensic Pathology},
  year = {2026},
  doi = {10.1177/19253621261477483},
  url = {https://doi.org/10.1177/19253621261477483}
}

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