Systemic Sclerosis and Related Diseases Open access Peer reviewed

Gastrointestinal tract involvement in systemic sclerosis

Р. Т. Алекперов

Modern Rheumatology Journal | Jun 24, 2026

Abstract

Abstract

Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by generalized microangiopathy and fibrosis of the skin and internal organs. The gastrointestinal (GI) tract is the most frequently affected organ system in SSc, and signs of GI involvement often occur at early stages of the disease. Currently, approved treatment options for GI involvement in SSc are limited, while approaches to treatment of different GI segments’ differ fundamentally. Despite its high prevalence, gastroenterological complications of SSc are insufficiently covered in the literature. This review analyzes current methods for the diagnosis and treatment of GI involvement in SSc.

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Р. Т. Алекперов

first | Regional Clinical Research | ORCID 0000-0002-9134-9624

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@article{2026Gastrointestinal,
  title = {Gastrointestinal tract involvement in systemic sclerosis},
  author = {Р. Т. Алекперов},
  journal = {Modern Rheumatology Journal},
  year = {2026},
  doi = {10.14412/1996-7012-2026-2-72-77},
  url = {https://doi.org/10.14412/1996-7012-2026-2-72-77}
}

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