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In this meta-analysis including individual-patient data from five randomized trials, beta-blocker therapy did not reduce the incidence of death from any cause, myocardial infarction, or heart failure in patients with an LVEF of at least 50% after myocardial infarction without other indications for beta-blockers.
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In this meta-analysis including individual-patient data from five randomized trials, beta-blocker therapy did not reduce the incidence of death from any cause, myocardial infarction, or heart failure in patients with an LVEF of at least 50% after myocardial infarction without other indications for beta-blockers. (Funded by Centro Nacional de Investigaciones Cardiovasculares Carlos III and others; PROSPERO database number, CRD420251119176.).
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@article{Karlstrm2025Beta,
title = {Beta-Blockers after Myocardial Infarction with Normal Ejection Fraction},
author = {Patric Karlström and Arnhild Bakken and Stuart Pocock and Anna Meta Dyrvig Kristensen and Xavier Rosselló and Dan Atar and Troels Yndigegn and Takeshi Kimura and Roberto Latini and Bertil Lindahl and Michael Hecht Olsen and Valentı́n Fuster and Robin Hofmann and Kjell Vikenes and Michael Mæng and David Erlinge and Theis Lange and José A. Barrabés and Jocelyne R. Benatar and Sergio Raposeiras‐Roubín and Claes Held and Massimo Piepoli and Morten Wang Fagerland and Therese Lucia Friis Holmager and Neiko Ozasa and Eva Prescott and John Munkhaugen and Tomas Jernberg and Borja Ibáñez},
journal = {New England Journal of Medicine},
year = {2025},
doi = {10.1056/nejmoa2512686},
url = {https://doi.org/10.1056/nejmoa2512686}
}
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