Cardiac Valve Diseases and Treatments
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Kidney impairment potentially has substantial prognostic impact and should be incorporated into lifetime TAVI patient management.
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Abstract Background Prognosis after transcatheter aortic valve implantation (TAVI) keeps improving, yet some high-risk groups persist with chronic kidney disease being one. Contemporary data on the prognostic importance of pre-TAVI kidney function are sparse, leaving uncertainty regarding which patients derive limited benefit from TAVI. Aim To describe the association between pre-procedural kidney function and long-term outcomes in TAVI patients. Methods We used Danish nationwide registries to identify patients with aortic stenosis undergoing TAVI between 2015 and end 2022. Patients were categorized by baseline eGFR: ≥60, 30-59, and 14 days after TAVI was most frequent among patients with eGFR <30 or dialysis (18.4%). Conclusion We observed a stepwise association between pre-TAVI kidney function and post-TAVI one-year mortality as well as hospitalization burden. Kidney impairment potentially has substantial prognostic impact and should be incorporated into lifetime TAVI patient management.
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@article{Meibom2026Prognostic,
title = {Prognostic Impact of Kidney Function before Transcatheter Aortic Valve Implantation - A Nationwide study},
author = {Martha Meibom and Jeppe Kofoed Petersen and Victoria Mikkelsen and Louise Marqvard Sørensen and Jonas Agerlund Povlsen and Christian Juhl Terkelsen and Ashkan Eftekhari and Ole de Backer and Morten Schou and Lars Køber and Emil Fosbøl},
journal = {European Heart Journal - Valvular and Structural Heart Disease},
year = {2026},
doi = {10.1093/ehjvshd/xwag074},
url = {https://doi.org/10.1093/ehjvshd/xwag074}
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