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Carobs’ impact on human health: a narrative review

Daniela Bonofilgio, Ioanna Tsiligianni, Antonios Koutelidakis, Maria Hassapidou and 23 more

Natural Product Research | Jul 23, 2026

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What this paper is about

The review highlights carobs as a natural functional food rich in bioactive compounds, with evidence from human, animal, and experimental studies suggesting potential beneficial effects on gastrointestinal, cardiovascular, endocrine, reproductive, and metabolic health.

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). The aim of this narrative review was to summarise the current scientific knowledge on carobs, regarding their impact on human health and possible associated benefits. A comprehensive literature search was conducted in the electronic database of Medline/PubMed to identify original studies and/or randomised controlled trials (RCTs) reporting on the impact of carobs on different aspects of human health. The review elucidated several potentially favourable effects of carobs, attributed to their rich content of bioactive compounds, such as insoluble fibres, polyphenols, flavonoids, tannins, and D-pinitol. The review highlights carobs as a natural functional food rich in bioactive compounds, with evidence from human, animal, and experimental studies suggesting potential beneficial effects on gastrointestinal, cardiovascular, endocrine, reproductive, and metabolic health. However, the strength of evidence varies across outcomes, and further well-designed clinical studies are needed to confirm these findings.

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Authors

Researchers on this paper

Daniela Bonofilgio

first | University of Calabria

Ioanna Tsiligianni

middle | University of Crete

Antonios Koutelidakis

middle | Unité de Nutrition Humaine

Maria Hassapidou

middle | International Hellenic University | ORCID 0000-0003-1027-5772

Anna Horňáková

middle | National Institute Of Hygiene And Epidemiology | ORCID 0000-0002-1024-8056

Iffat Elbarazi

middle | United Arab Emirates University

Olga Papagianni

middle | Unité de Nutrition Humaine | ORCID 0000-0003-0026-0630

Eliza Markidou

middle | Open University of Cyprus

Fabiana Maria Pia Albergati

middle | University of Calabria

Sevasti Peraki

middle | University of Crete | ORCID 0009-0004-1516-7126

Jana Bohumska

middle | National Institute Of Hygiene And Epidemiology

Agoritsa Kovani

middle | Unité de Nutrition Humaine

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Citation

BibTeX

@article{Bonofilgio2026Carobs,
  title = {Carobs’ impact on human health: a narrative review},
  author = {Daniela Bonofilgio and Ioanna Tsiligianni and Antonios Koutelidakis and Maria Hassapidou and Anna Horňáková and Iffat Elbarazi and Olga Papagianni and Eliza Markidou and Fabiana Maria Pia Albergati and Sevasti Peraki and Jana Bohumska and Agoritsa Kovani and Antria Kourti and Georgia Angelopoulou and Maria Agiasoti and Barbora Hanžlová and Karolína Hrubešová and Ioanna Fakiri and Maria Bissia and Monika Zamolova and Dimitra Karafyllaki and Alexandros Grammenos and L Kuzelová and Kyriaki Petridou and Marta Anna Madrigrano and A Pilati and Soteriades,, Elpidoforos S.},
  journal = {Natural Product Research},
  year = {2026},
  doi = {10.1080/14786419.2026.2704054},
  url = {https://doi.org/10.1080/14786419.2026.2704054}
}

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